Syndrome of Hajdu-Cheney: three case reports of orofacial interest.

Effect of Zoledronic Acid on Acro-Osteolysis and Osteoporosis in a Patient with Hajdu-Cheney Syndrome

Hajdu-Cheney syndrome is a rare, autosomal dominant skeletal dysplasia marked by acro-osteolysis of the distal phalanges and severe osteoporosis. Although there are more than 60 reports published to date, proper treatment and subsequent outcome have been scarce. Herein, we report a progress of anti-resorptive therapy with zoledronic acid, in a woman with Hajdu-Cheney syndrome. Results suggest t...

Hajdu-Cheney syndrome - a rare cause of micrognathia

A Novel Mutation of Notch homolog protein 2 gene in a Chinese Family with Hajdu-Cheney Syndrome

An Unusual Presentation of Diabetic Ketoacidosis in Familial Hajdu-Cheney Syndrome: A Case Report

A 21-year-old man with diabetic ketoacidosis (DKA) displayed short and clubbed fingers and marked eyebrow, which are typical of Hajdu-Cheney Syndrome (HCS). Laboratory findings confirmed type 1 diabetes mellitus (DM). After conservative care with hydration and insulin supply, metabolic impairment was improved. Examinations of bone and metabolism revealed osteoporosis and craniofacial abnormalit...

A patient with acro-osteolysis syndrome: Hajdu-Cheney.

Hajdu-Cheney syndrome is an autosomal dominant acroosteolysis syndrome, in which clinical and radiological abnormalities develop at different stages of life. A 26-year-old woman visited our rheumatology clinic for progressive shortening of her terminal phalanges. Radiographs showed acro-osteolysis and classic midphalangeal band-like resorption of the terminal phalanges affecting multiple digits...